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Article

Yeast TAF(II)90 is required for cell-cycle progression through G2/M but not for general transcription activation.

Genes & development - 15 Sept 1996

Apone L M, Virbasius C M, Reese J C, Green M R

Abstract excerpt

The RNA polymerase II general transcription factor TFIID is a multisubunit complex comprising TATA-box binding protein and associated factors (TAFIIs). In vitro experiments have suggested that TAFIIs are essential coactivators required for RNA polymerase II-directed transcription activation. Here, for the first time, we analyze systematically the in vivo function of a specific TAFII, yeast TAFII90 (yTAFII90). We...

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Identifiers

PMID: 8824595
DOI: 10.1101/gad.10.18.2368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Yeast TAF(II)90 is required for cell-cycle progression through G2/M but not for general transcription activation.PMID 8824595Read ↗

Distinct mutations in yeast TAF(II)25 differentially affect the composition of TFIID and SAGA complexes as well as global gene expression patterns.Semantic proximity Read ↗

Transcription activation in cells lacking TAFIIS.Semantic proximity Read ↗

Broad, but not universal, transcriptional requirement for yTAFII17, a histone H3-like TAFII present in TFIID and SAGA.Semantic proximity Read ↗

Analysis of TAF90 mutants displaying allele-specific and broad defects in transcription.Semantic proximity Read ↗

Systematic analysis of essential yeast TAFs in genome-wide transcription and preinitiation complex assembly.Semantic proximity Read ↗

TBP-associated factors are not generally required for transcriptional activation in yeast.Semantic proximity Read ↗

Genome-wide localization analysis of a complete set of Tafs reveals a specific effect of the taf1 mutation on Taf2 occupancy and provides indirect evidence for different TFIID conformations at different promoters.Semantic proximity Read ↗

Region of yeast TAF 130 required for TFIID to associate with promoters.Semantic proximity Read ↗

TFIIA interacts with TFIID via association with TATA-binding protein and TAF40.Semantic proximity Read ↗

Requirement for TAF(II)250 acetyltransferase activity in cell cycle progression.Semantic proximity Read ↗

Kin28 depletion increases association of TFIID subunits Taf1 and Taf4 with promoters in Saccharomyces cerevisiae.Semantic proximity Read ↗

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