Article
Therapeutic interventions in mice with chronic proliferative dermatitis (cpdm/cpdm).
Experimental dermatology - 1 Oct 2000
Gijbels M J, Elliott G R, HogenEsch H, Zurcher C, van den Hoven A, Bruijnzeel P L
Abstract excerpt
Chronic proliferative dermatitis (cpd) is a spontaneous mutation in C57BL/Ka mice (cpdm/cpdm). The dermatitis is characterized by redness, hairloss, scaling, pruritus and histologically by epithelial hyperproliferation, infiltration of eosinophils, macrophages and mast cells. Lesions similar to those in the skin occur in the esophagus and forestomach. In this paper, we describe the effect of drug treatments...
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