Article
A spontaneous mutation characterized by chronic proliferative dermatitis in C57BL mice.
The American journal of pathology - 1 Sept 1993
HogenEsch H, Gijbels M J, Offerman E, van Hooft J, van Bekkum D W, Zurcher C
Abstract excerpt
Chronic proliferative dermatitis is a new spontaneous mutation in C57BL/Ka mice. Breeding results suggest an autosomal recessive mode of inheritance. Mutant mice develop skin lesions at the age of 5 to 6 weeks. The lesions occur in the ventral and dorsal skin of the body, whereas ears, footpads,...
Topics
- Adrenal Cortex Hormones
- Animals
- Chronic Disease
- Cyclosporine
- Dermatitis
- Disease Models, Animal
- Immunohistochemistry
- Mast Cells
- Mice
- Mice, Inbred C57BL
- Mutation
- Rodent Diseases
- Skin