Article
A spontaneous mutation characterized by chronic proliferative dermatitis in C57BL mice.
The American journal of pathology - 1 Sept 1993
HogenEsch H, Gijbels M J, Offerman E, van Hooft J, van Bekkum D W, Zurcher C
Abstract excerpt
Chronic proliferative dermatitis is a new spontaneous mutation in C57BL/Ka mice. Breeding results suggest an autosomal recessive mode of inheritance. Mutant mice develop skin lesions at the age of 5 to 6 weeks. The lesions occur in the ventral and dorsal skin of the body, whereas ears, footpads, and tail are not involved. The lesions are characterized by epidermal hyperplasia, hyper- and parakeratosis, and single...
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