Factor V Q506 (resistance to activated protein C) and prognosis after acute coronary syndrome.

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Article

Factor V Q506 (resistance to activated protein C) and prognosis after acute coronary syndrome.

Thrombosis and haemostasis - 1 Jun 1999

Holm J, Hillarp A, Zöller B, Erhardt L, Berntorp E, Dahlbäck B

Abstract excerpt

Factor V:Q506 causing resistance to activated protein C (APC-resistance), is a risk factor for venous thrombosis. Some studies have indicated an association with arterial disease, especially in women. We investigated the prevalence of the FV:Q506 allele prospectively in 295 patients with acute coronary syndrome. Mortality and myocardial infarction rate were evaluated after 30 days and after 2 years. The FV:Q506...

Topics

Activated Protein C Resistance
Acute Disease
Aged
Alleles
Coronary Disease
Factor V
Female
Humans
Male
Middle Aged
Mutation
Polymorphism, Genetic
Prevalence
Prognosis
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 10404756

Genes

Provenance

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