Article
Factor V Leiden (resistance to activated protein C) increases the risk of myocardial infarction in young women.
Blood - 15 Apr 1997
Rosendaal F R, Siscovick D S, Schwartz S M, Beverly R K, Psaty B M, Longstreth W T, Raghunathan T E, Koepsell T D, Reitsma P H
Abstract excerpt
Factor V Leiden (factor V Arg506Gln), the genetic defect underlying resistance to activated protein C, is the most common risk factor for venous thrombosis. The relationship between this genetic abnormality and arterial disease is still unresolved. To assess whether factor V Leiden increases the risk of myocardial infarction (MI), we conducted a population-based case-control study among women 18 to 44 years of...
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