Article
Further evidence for anticipation in schizophrenia.
Psychiatry research - 29 Nov 1995
Thibaut F, Martinez M, Petit M, Jay M, Campion D
Abstract excerpt
The term 'anticipation' is used to describe the increase in disease severity or the decrease in age of onset in succeeding generations within families. This phenomenon has been related to expansion of trinucleotide repeat DNA sequences in some genetic illnesses. We examined age of onset among two generations in familial schizophrenia. Twenty-six unilineal pedigrees previously ascertained for linkage studies were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
