Article
Anticipation in unipolar affective disorder.
Journal of affective disorders - 9 Oct 1995
Engström C, Thornlund A S, Johansson E L, Långström M, Chotai J, Adolfsson R, Nylander P O
Abstract excerpt
Anticipation describes an inheritance pattern within a pedigree with an increase in disease severity and/or decrease in age at onset in successive generations. The phenomenon of anticipation has recently been shown to be correlated with the expansion of trinucleotide repeat sequences in a neuromuscular disease, various neurodegenerative disorders and mental retardation. We have studied parent-offspring...
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