Article
The Gln-Arg191 polymorphism of the human paraoxonase gene (HUMPONA) is not associated with the risk of coronary artery disease in Finns.
The Journal of clinical investigation - 15 Aug 1996
Antikainen M, Murtomäki S, Syvänne M, Pahlman R, Tahvanainen E, Jauhiainen M, Frick M H, Ehnholm C
Abstract excerpt
The human paraoxonase gene (HUMPONA) is codominantly expressed as alleles A and G. The A allele codes for glutamine (A genotype) and the G allele for arginine (B genotype) at position 191 of the paraoxonase enzyme. This genetic polymorphism has been suggested to be associated with the predisposit...
Topics
- Adult
- Alleles
- Aryldialkylphosphatase
- Base Sequence
- Coronary Disease
- DNA Primers
- Esterases
- Female
- Finland
- Gene Frequency
- Humans
- Male
- Molecular Sequence Data
- Polymorphism, Genetic