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Article

The Gln-Arg191 polymorphism of the human paraoxonase gene (HUMPONA) is not associated with the risk of coronary artery disease in Finns.

The Journal of clinical investigation - 15 Aug 1996

Antikainen M, Murtomäki S, Syvänne M, Pahlman R, Tahvanainen E, Jauhiainen M, Frick M H, Ehnholm C

Abstract excerpt

The human paraoxonase gene (HUMPONA) is codominantly expressed as alleles A and G. The A allele codes for glutamine (A genotype) and the G allele for arginine (B genotype) at position 191 of the paraoxonase enzyme. This genetic polymorphism has been suggested to be associated with the predisposition to coronary artery disease (CAD). We investigated the frequency of paraoxonase A and G alleles in 380...

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Identifiers

PMID: 8770857
DOI: 10.1172/JCI118869
PMCID: PMC507500

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Gln-Arg191 polymorphism of the human paraoxonase gene (HUMPONA) is not associated with the risk of coronary artery disease in Finns.PMID 8770857Read ↗

The gln-Arg192 polymorphism of human paraoxonase gene is not associated with coronary artery disease in italian patients.Semantic proximity Read ↗

The Gln-Arg 191 polymorphism of the human paraoxonase gene is not associated with the risk of coronary artery disease among Chinese in Taiwan.Semantic proximity Read ↗

A variant of human paraoxonase/arylesterase (HUMPONA) gene is a risk factor for coronary artery disease.Semantic proximity Read ↗

The human paraoxonase Gln-Argl92 (Q/R) polymorphism in turkish patients with coronary artery disease.Semantic proximity Read ↗

A 192Arg variant of the human paraoxonase (HUMPONA) gene polymorphism is associated with an increased risk for coronary artery disease in the Japanese.Semantic proximity Read ↗

[The paraoxonase Gln-Arg192 polymorphism in patients with coronary heart disease in Chinese population].Semantic proximity Read ↗

The Gln/Arg polymorphism of human paraoxonase (PON 192) is not related to myocardial infarction in the ECTIM Study.Semantic proximity Read ↗

The paraoxonase Gln-Arg 192 polymorphism in subjects with ischaemic heart disease.Semantic proximity Read ↗

Human paraoxonase 1 gene polymorphisms and the risk of coronary heart disease: a community-based study.Semantic proximity Read ↗

Paraoxonase Arg 192 allele is an independent risk factor for three-vessel stenosis of coronary artery disease.Semantic proximity Read ↗

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Mutations in the human paraoxonase 1 gene: frequencies, allelic linkages, and association with coronary artery disease.Semantic proximity Read ↗

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