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Article

Susceptibility to Reiter's syndrome is associated with alleles of TAP genes.

Arthritis and rheumatism - 1 May 1995

Barron K S, Reveille J D, Carrington M, Mann D L, Robinson M A

Abstract excerpt

OBJECTIVE: Although HLA-B27 is strongly associated with susceptibility to Reiter's syndrome (RS), recent data suggest that an additional modifying or susceptibility gene(s) acts in concert with HLA-B27 to contribute to disease pathogenesis. The recently described TAP genes (transporters associated with antigen processing) are potential candidates because they are polymorphic and their function is to transport...

Topics

ATP-Binding Cassette Transporters
Alleles
Arthritis, Reactive
Base Sequence
Disease Susceptibility
Genetic Linkage
HLA-B27 Antigen
Humans
Molecular Sequence Data

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7748224
DOI: 10.1002/art.1780380517

Genes

TAP1
TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7748224-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Susceptibility to Reiter's syndrome is associated with alleles of TAP genes.PMID 7748224Read ↗

TAP1 and TAP2 polymorphism in HLA-B27-positive subpopulations: no allelic differences in ankylosing spondylitis and reactive arthritis.Semantic proximity Read ↗

TAP1 and TAP2 polymorphism in Spanish patients with ankylosing spondylitis.Semantic proximity Read ↗

TAP2D is associated with HLA-B44 and DR4 and may contribute to rheumatoid arthritis and Felty's syndrome susceptibility.Semantic proximity Read ↗

Tap gene associations in UK caucasoids.Semantic proximity Read ↗

TAP1 and TAP2 gene polymorphisms in Korean patients with allergic rhinitis.Semantic proximity Read ↗

Polymorphism of human major histocompatibility complex-encoded transporter associated with antigen processing (TAP) genes and susceptibility to juvenile rheumatoid arthritis.Semantic proximity Read ↗

Genetic polymorphisms in MHC-encoded antigen processing gene TAP2: a case-control study in end-stage renal disease patients of North India.Semantic proximity Read ↗

Specificities of human TAP alleles for HLA-B27 binding peptides.Semantic proximity Read ↗

TAP gene transporter polymorphism in inflammatory bowel diseases.Semantic proximity Read ↗

Frequency of HLA-B27 and its alleles in patients with Reiter syndrome: comparison with the frequency in other spondyloarthropathies and a healthy control population.Semantic proximity Read ↗

Comparison of TAP2 frequencies in type 1 diabetes patients and healthy controls from three ethnic groups indicates an African origin for the TAP2 G allele.Semantic proximity Read ↗

Genotyping TAP2 variants in North American Caucasians, Brazilians, and Africans.Semantic proximity Read ↗

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