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Article

Peptide transporter genes (TAP) polymorphisms and genetic susceptibility to rheumatoid arthritis.

British journal of rheumatology - 1 Mar 1995

Vandevyver C, Geusens P, Cassiman J J, Raus J

Abstract excerpt

The association of rheumatoid arthritis (RA) with HLA-DRB1 alleles indicates that at least one RA susceptibility gene is linked to the HLA class II region. Transporter associated with protein processing (TAP) genes, which lie upstream of the HLA-structural genes, may also contribute to disease susceptibility. We investigated polymorphisms of the peptide transporter genes, TAP 1 and TAP 2, by PCR-ASO hybridization...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Arthritis, Rheumatoid
Base Sequence
Disease Susceptibility
Female
Genes, MHC Class I
HLA-DR Antigens
HLA-DRB1 Chains
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Molecular Sequence Data

Polymorphism, Genetic

Source

Identifiers

PMID: 7728393
DOI: 10.1093/rheumatology/34.3.207

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7728393-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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