Article
Elevation of growth hormone secretagogue receptor type 1a mRNA expression in human growth hormone-secreting pituitary adenoma harboring G protein alpha subunit mutation.
Neuro endocrinology letters - 1 Jan 2010
Xu Tongjiang, Ye Fei, Wang Baofeng, Tian Chunlei, Wang Sheng, Shu Kai, Guo Dongsheng, Lei Ting
Abstract excerpt
OBJECTIVE: The purpose of this study was to investigate the relationship between the ghrelin or GHSR-1a mRNA levels and clinical characteristics and to confirm the effect of gsp mutations on ghrelin/GHSR-1a system in human GH-secreting pituitary adenomas. METHODS: The expression levels of ghrelin, GHSR-1a mRNA were determined by SYBR green real-time fluorescent quantitative PCR. The gsp mutations in 43 cases of...
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