Article
The MDR phenotype in hematologic malignancies: prognostic relevance and future perspectives.
Annals of hematology - 1 Mar 1996
Hegewisch-Becker S, Hossfeld D K
Abstract excerpt
The multidrug resistant (MDR) phenotype has been suspected as a major cause of treatment failure in hematologic malignancies. Numerous studies have investigated the expression of the MDR1 gene product, P-glycoprotein, in leukemia, lymphoma and myeloma. Studies in myelogenous leukemia and myeloma...
Topics
- Drug Resistance, Multiple
- Forecasting
- Gene Expression
- Humans
- Idarubicin
- Leukemia
- Lymphoma
- Multiple Myeloma
- Phenotype
- Prognosis