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Article

Transimmortalized mouse intestinal cells (m-ICc12) that maintain a crypt phenotype.

The American journal of physiology - 1 Jun 1996

Bens M, Bogdanova A, Cluzeaud F, Miquerol L, Kerneis S, Kraehenbuhl J P, Kahn A, Pringault E, Vandewalle A

Abstract excerpt

This study describes the properties of a clone of immortalized cells (m-ICc12 cells) derived from the bases of small intestinal villi from 20-day-old fetuses of L-type pyruvate kinase (L-PK)/ TAg1 transgenic mice. The mice harbor the simian virus 40 large T antigen under the control of the 5' regulatory sequence from the L-PK gene. m-ICc12 cells expressed nuclear large T antigen, had a prolonged life span, and...

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Identifiers

PMID: 8764149
DOI: 10.1152/ajpcell.1996.270.6.C1666

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