Article
Separate sexes and the mitochondrial theory of ageing.
Journal of theoretical biology - 21 May 1996
Allen J F
Abstract excerpt
An hypothesis is presented by which gamete specialization resolves a conflict between the function and replication of mitochondria. The function of mitochondria is to synthesize ATP by oxidative phosphorylation, which is coupled to respiratory electron transport. This requires a mitochondrial genetic system. However, "incorrect" electron transfers produce free radicals that cause mutation, and the frequency of...
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