Article
Ccl1, a cyclin associated with protein kinase Kin28, controls the phosphorylation of RNA polymerase II largest subunit and mRNA transcription.
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie - 1 Mar 1996
Valay J G, Dubois M F, Bensaude O, Faye G
Abstract excerpt
The Kin28 protein kinase interacts physically and genetically with cyclin Ccl1. Kin28 has been reported recently to be involved in the in vivo phosphorylation of the largest subunit of RNA polymerase II (Rpb1) in Saccharomyces cerevisiae. Now, we show that in a strain harboring a conditional ccl1...
Topics
- Cyclins
- Fungal Proteins
- In Vitro Techniques
- Mutation
- Peptide Chain Termination, Translational
- Phosphorylation
- Protein Serine-Threonine Kinases
- RNA Polymerase II
- RNA, Messenger
- Saccharomyces cerevisiae
- Temperature