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Article

The kin28 protein kinase is associated with a cyclin in Saccharomyces cerevisiae.

Journal of molecular biology - 20 Nov 1993

Valay J G, Simon M, Faye G

Abstract excerpt

Kin28 is an essential serine-threonine kinase of Saccharomyces cerevisiae. Multicopies of a novel cyclin gene, CCL1, are able to suppress the thermosensitivity of two kin28-ts mutants. The CCL1 gene is not cyclically transcribed, yet its product is also essential for cell proliferation. Furthermo...

Topics

Alleles
Amino Acid Sequence
Base Sequence
Cell Cycle
Cyclin-Dependent Kinases
Cyclins
Fungal Proteins
Genes, Fungal
Molecular Sequence Data
Mutation
Protein Serine-Threonine Kinases
Saccharomyces cerevisiae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae Proteins

Sequence Homology, Amino Acid

Suppression, Genetic

Source

Identifiers

PMID: 8230216
DOI: 10.1006/jmbi.1993.1587

Genes

CCL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8230216-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Click a neighbor to travelStep 1 · 12 closest

The kin28 protein kinase is associated with a cyclin in Saccharomyces cerevisiae.PMID 8230216Read ↗

Ccl1, a cyclin associated with protein kinase Kin28, controls the phosphorylation of RNA polymerase II largest subunit and mRNA transcription.Semantic proximity Read ↗

Cak1 is required for Kin28 phosphorylation and activation in vivo.Semantic proximity Read ↗

The KIN28 gene is required both for RNA polymerase II mediated transcription and phosphorylation of the Rpb1p CTD.Semantic proximity Read ↗

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A phosphorylation-independent role for the yeast cyclin-dependent kinase activating kinase Cak1.Semantic proximity Read ↗

CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae.Semantic proximity Read ↗

Mutational analysis of Cak1p, an essential protein kinase that regulates cell cycle progression.Semantic proximity Read ↗

Comparison of the Saccharomyces cerevisiae G1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins.Semantic proximity Read ↗

Physical interaction of Cdc28 with Cdc37 in Saccharomyces cerevisiae.Semantic proximity Read ↗

The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex.Semantic proximity Read ↗

The cloning and characterization of the CDC50 gene family in Saccharomyces cerevisiae.Semantic proximity Read ↗

CDC68, a yeast gene that affects regulation of cell proliferation and transcription, encodes a protein with a highly acidic carboxyl terminus.Semantic proximity Read ↗

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