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Article

The kin28 protein kinase is associated with a cyclin in Saccharomyces cerevisiae.

Journal of molecular biology - 20 Nov 1993

Valay J G, Simon M, Faye G

Abstract excerpt

Kin28 is an essential serine-threonine kinase of Saccharomyces cerevisiae. Multicopies of a novel cyclin gene, CCL1, are able to suppress the thermosensitivity of two kin28-ts mutants. The CCL1 gene is not cyclically transcribed, yet its product is also essential for cell proliferation. Furthermore, when overexpressed under high expression promoter, Cell is able to replace G1 function of Cln cyclins. Cell and...

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Source

Identifiers

PMID: 8230216
DOI: 10.1006/jmbi.1993.1587

Genes

CCL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The kin28 protein kinase is associated with a cyclin in Saccharomyces cerevisiae.PMID 8230216Read ↗

Ccl1, a cyclin associated with protein kinase Kin28, controls the phosphorylation of RNA polymerase II largest subunit and mRNA transcription.Semantic proximity Read ↗

Cak1 is required for Kin28 phosphorylation and activation in vivo.Semantic proximity Read ↗

The KIN28 gene is required both for RNA polymerase II mediated transcription and phosphorylation of the Rpb1p CTD.Semantic proximity Read ↗

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A phosphorylation-independent role for the yeast cyclin-dependent kinase activating kinase Cak1.Semantic proximity Read ↗

CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae.Semantic proximity Read ↗

Mutational analysis of Cak1p, an essential protein kinase that regulates cell cycle progression.Semantic proximity Read ↗

Comparison of the Saccharomyces cerevisiae G1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins.Semantic proximity Read ↗

Physical interaction of Cdc28 with Cdc37 in Saccharomyces cerevisiae.Semantic proximity Read ↗

The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex.Semantic proximity Read ↗

The cloning and characterization of the CDC50 gene family in Saccharomyces cerevisiae.Semantic proximity Read ↗

CDC68, a yeast gene that affects regulation of cell proliferation and transcription, encodes a protein with a highly acidic carboxyl terminus.Semantic proximity Read ↗

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