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Article

The KIN28 gene is required both for RNA polymerase II mediated transcription and phosphorylation of the Rpb1p CTD.

Journal of molecular biology - 9 Jun 1995

Valay J G, Simon M, Dubois M F, Bensaude O, Facca C, Faye G

Abstract excerpt

Kin28p, associated with cyclin Ccl1p, is a putative cyclin-dependent kinase (CDK) of the p34cdc2 family in Saccharomyces cerevisiae. Search for mutations co-lethal (syn mutations) with a kin28 thermosensitive mutation (kin28-ts3) has uncovered genetic interactions between gene KIN28 and genes RAD3, SIN4, STI1 and CDC37. The genetic interaction between KIN28 and the CDC37 cell division cycle gene suggests that a...

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Source

Identifiers

PMID: 7783209
DOI: 10.1006/jmbi.1995.0316

Genes

CDC37

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The KIN28 gene is required both for RNA polymerase II mediated transcription and phosphorylation of the Rpb1p CTD.PMID 7783209Read ↗

Ccl1, a cyclin associated with protein kinase Kin28, controls the phosphorylation of RNA polymerase II largest subunit and mRNA transcription.Semantic proximity Read ↗

Rig2, a RING finger protein that interacts with the Kin28/Ccl1 CTD kinase in yeast.Semantic proximity Read ↗

The kin28 protein kinase is associated with a cyclin in Saccharomyces cerevisiae.Semantic proximity Read ↗

Cak1 is required for Kin28 phosphorylation and activation in vivo.Semantic proximity Read ↗

CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae.Semantic proximity Read ↗

Cell cycle-dependent phosphorylation of the DNA polymerase epsilon subunit, Dpb2, by the Cdc28 cyclin-dependent protein kinase.Semantic proximity Read ↗

Yeast counterparts of subunits S5a and p58 (S3) of the human 26S proteasome are encoded by two multicopy suppressors of nin1-1.Semantic proximity Read ↗

The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex.Semantic proximity Read ↗

Budding yeast CTDK-I is required for DNA damage-induced transcription.Semantic proximity Read ↗

Kin28, the TFIIH-associated carboxy-terminal domain kinase, facilitates the recruitment of mRNA processing machinery to RNA polymerase II.Semantic proximity Read ↗

MPK1/SLT2 Links Multiple Stress Responses with Gene Expression in Budding Yeast by Phosphorylating Tyr1 of the RNAP II CTD.Semantic proximity Read ↗

Engineered Covalent Inactivation of TFIIH-Kinase Reveals an Elongation Checkpoint and Results in Widespread mRNA Stabilization.Semantic proximity Read ↗

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