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Article

Cytotoxic T-lymphocyte responses to HIV-1 reverse transcriptase (review).

Viral immunology - 1 Jan 1998

Menéndez-Arias L, Mas A, Domingo E

Abstract excerpt

Cytotoxic T lymphocytes (CTL) play an important role in the control of human immunodeficiency virus (HIV) infection. CTL responses have been demonstrated for most of the HIV gene products, predominantly gag, pol, and env-encoded proteins, and also for the regulatory proteins Nef, Tat, Vif, or Rev. The HIV-1 reverse transcriptase (RT), which derives from expression of the pol gene, is an important target of...

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Identifiers

PMID: 10189185
DOI: 10.1089/vim.1998.11.167

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