Article
Accelerated disappearance of melanocytes in bcl-2-deficient mice.
Cancer research - 1 Aug 1996
Yamamura K, Kamada S, Ito S, Nakagawa K, Ichihashi M, Tsujimoto Y
Abstract excerpt
Follicular melanocytes in bcl-2(-/-) mice have been reported to turn gray during the second hair cycle. Light microscopic analysis revealed that about half of bcl-2(-/-) mouse hair shafts had no detectable melanin granules after the second hair follicle cycle, but the remaining hair appeared to be pigmented normally. After depilation to induce new anagen hair, more than 97% of the hair shafts did not have visible...
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