Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jan 2007

Schouwey Karine, Delmas Véronique, Larue Lionel, Zimber-Strobl Ursula, Strobl Lothar J, Radtke Freddy, Beermann Friedrich

Abstract excerpt

The Notch signaling pathway is involved in diverse biological processes such as cell fate decisions or stem cell maintenance. In this study, we assessed the role of this pathway for melanocyte development and hair pigmentation using RBP-Jkappa, Notch1, and Notch2 conditional knockout mice. Disrup...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Lineage
Share to Embryo, Mammalian
Share to Hair Color

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hair Follicle

Share to Intramolecular Oxidoreductases

Share to Melanocytes

Share to Receptor, Notch1

Share to Receptor, Notch2

Source

Identifiers

PMID: 17080428
DOI: 10.1002/dvdy.21000

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17080428-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner.PMID 17080428Read ↗

Both Notch1 and Notch2 contribute to the regulation of melanocyte homeostasis.Semantic proximity Read ↗

Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentationSemantic proximity Read ↗

Aging, graying and loss of melanocyte stem cells.Semantic proximity Read ↗

Understanding Melanocyte Stem Cells for Disease Modeling and Regenerative Medicine ApplicationsSemantic proximity Read ↗

Human hair greying is linked to a specific depletion of hair follicle melanocytes affecting both the bulb and the outer root sheathSemantic proximity Read ↗

BRN2 suppresses stress-induced hair greyingSemantic proximity Read ↗

Generation of Pmel-dependent conditional and inducible Cre-driver mouse line for melanocytic-targeted gene manipulation.Semantic proximity Read ↗

A review of genetic disorders of hypopigmentation: lessons learned from the biology of melanocytesSemantic proximity Read ↗

[Melanocyte stem cells in adults].Semantic proximity Read ↗

Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair FollicleSemantic proximity Read ↗

The cell biology of human hair follicle pigmentationSemantic proximity Read ↗

Stem cell factor–KIT signalling plays a pivotal role in regulating pigmentation in mammalian hairSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.