Article
A widespread transposable element masks expression of a yeast copper transport gene.
Genes & development - 1 Aug 1996
Knight S A, Labbé S, Kwon L F, Kosman D J, Thiele D J
Abstract excerpt
The trace element copper (Cu) is essential for cell growth. In this report we describe the identification of a new component of the high-affinity Cu transport machinery in yeast, encoded by the CTR3 gene. Ctr3p is a small intracellular cysteine-rich integral membrane protein that restores high-affinity Cu uptake, Cu, Zn superoxide dismutase activity, ferrous iron transport, and respiratory proficiency to strains...
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