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Article

Eukaryotic CTR copper uptake transporters require two faces of the third transmembrane domain for helix packing, oligomerization, and function.

The Journal of biological chemistry - 17 Dec 2004

Aller Stephen G, Eng Edward T, De Feo Christopher J, Unger Vinzenz M

Abstract excerpt

Members of the copper uptake transporter (CTR) family from yeast, plants, and mammals including human are required for cellular uptake of the essential metal copper. Based on biochemical data, CTRs have three transmembrane domains and have been shown to oligomerize in the membrane. Among individual members of the family, there is little amino acid sequence identity, raising questions as to how these proteins...

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Identifiers

PMID: 15385536
DOI: 10.1074/jbc.M409421200
PMCID: PMC1201109

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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