Article
Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America - 23 Jul 1996
Lieberman M W, Wiseman A L, Shi Z Z, Carter B Z, Barrios R, Ou C N, Chévez-Barrios P, Wang Y, Habib G M, Goodman J C, Huang S L, Lebovitz R M, Matzuk M M
Abstract excerpt
gamma-Glutamyl transpeptidase (GGT) is an ectoenzyme that catalyzes the first step in the cleavage of glutathione (GSH) and plays an essential role in the metabolism of GSH and GSH conjugates of carcinogens, toxins, and eicosanoids. To learn more about the role of GGT in metabolism in vivo, we us...
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