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Article

P-OTX: a PIT-1-interacting homeodomain factor expressed during anterior pituitary gland development.

Proceedings of the National Academy of Sciences of the United States of America - 23 Jul 1996

Szeto D P, Ryan A K, O'Connell S M, Rosenfeld M G

Abstract excerpt

A novel OTX-related homeodomain transcription factor has been identified on the basis of its ability to interact with the transactivation domain of the pituitary-specific POU domain protein, Pit-1. This factor, referred to as P-OTX (pituitary OTX-related factor), is expressed in primordial Rathke's pouch, oral epithelium, first bronchial arch, duodenum, and hindlimb. In the developing anterior pituitary, it is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8755540
DOI: 10.1073/pnas.93.15.7706
PMCID: PMC38811

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P-OTX: a PIT-1-interacting homeodomain factor expressed during anterior pituitary gland development.PMID 8755540Read ↗

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Transcription factors regulating pituitary development.Semantic proximity Read ↗

Pituitary homeobox 2, a novel member of the bicoid-related family of homeobox genes, is a potential regulator of anterior structure formation.Semantic proximity Read ↗

Nuclear factor 1 and T-cell factor/LEF recognition elements regulate Pitx2 transcription in pituitary development.Semantic proximity Read ↗

PITX genes are required for cell survival and Lhx3 activation.Semantic proximity Read ↗

Candidate genes for panhypopituitarism identified by gene expression profiling.Semantic proximity Read ↗

A mutation in the POU-homeodomain of Pit-1 responsible for combined pituitary hormone deficiency.Semantic proximity Read ↗

Basic science and clinical research advances in the pituitary transcription factors: Pit-1 and Prop-1.Semantic proximity Read ↗

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