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Article

Nuclear factor 1 and T-cell factor/LEF recognition elements regulate Pitx2 transcription in pituitary development.

Molecular and cellular biology - 1 Aug 2007

Ai Di, Wang Jun, Amen Melanie, Lu Mei-Fang, Amendt Brad A, Martin James F

Abstract excerpt

Pitx2, a paired-related homeobox gene that is mutated in Rieger syndrome I, is the earliest known marker of oral ectoderm. Pitx2 was previously shown to be required for tooth, palate, and pituitary development in mice; however, the mechanisms regulating Pitx2 transcription in the oral ectoderm are poorly understood. Here we used an in vivo transgenic approach to investigate the mechanisms regulating Pitx2...

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Identifiers

PMID: 17562863
DOI: 10.1128/MCB.01848-06
PMCID: PMC1952127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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