Article
Delayed-type hypersensitivity in mast cell-deficient mice: dependence on platelets for expression of contact sensitivity.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jul 1996
Geba G P, Ptak W, Anderson G M, Paliwal V, Ratzlaff R E, Levin J, Askenase P W
Abstract excerpt
Previous studies of cutaneous T cell-mediated responses in mice have obtained pharmacologic, morphologic, and immunologic evidence pointing to a critical role for local mast cells in release of the vasoactive amine serotonin (5-HT) to mediate early, initiating events that are required for elicitation of these responses. However, the role of mast cells in initiating these T cell-mediated cutaneous responses has...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
