Article
Genetic heterogeneity in hereditary breast cancer: role of BRCA1 and BRCA2.
American journal of human genetics - 1 Sept 1996
Rebbeck T R, Couch F J, Kant J, Calzone K, DeShano M, Peng Y, Chen K, Garber J E, Weber B L
Abstract excerpt
The common hereditary forms of breast cancer have been largely attributed to the inheritance of mutations in the BRCA1 or BRCA2 genes. However, it is not yet clear what proportion of hereditary breast cancer is explained by BRCA1 and BRCA2 or by some other unidentified susceptibility gene(s). We describe the proportion of hereditary breast cancer explained by BRCA1 or BRCA2 in a sample of North American...
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