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Article

Constitutive expression of hepatic cytochrome P450 genes

1 Aug 1996

Abstract excerpt

Cytochromes P450 are a superfamily of heme proteins involved in oxidative metabolism of endogenous chemicals such as steroid hormones and human-made xenobiotics including drugs and environmental pollutants. Hundreds of P450s have been demonstrated by cDNA and gene cloning in animals, plants, fungi, and bacteria. Most of the mammalian xenobiotic-metabolizing P450s, found within the eight subfamilies comprising the...

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PMID: 8751713
DOI: 10.1096/fasebj.10.10.8751713

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