Article
Mini ReviewRole of Hepatocyte Nuclear Factors in Growth Hormone-regulated, Sexually Dimorphic Expression of Liver Cytochromes P450*
1 Jun 2004
Abstract excerpt
The liver is a sexually dimorphic organ in many species, including humans. In rodent models, dramatic sex differences characterize the expression of numerous plasma proteins, receptors and other signaling molecules, and enzymes of steroid and foreign compound metabolism, including members of the cytochrome P450 (CYP) superfamily. The sexual dimorphism of liver gene expression is dictated by the temporal pattern...
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