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Article

Immunohistochemical analysis of p53 mutations in bronchioloalveolar carcinoma and conventional pulmonary adenocarcinoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Dec 1995

Wang X, Rao M S, Yeldandi A V

Abstract excerpt

Mutations of p53 tumor suppressor gene have been shown to contribute to tumorigenesis in a variety of human cancers. Normally, p53 protein degrades rapidly and is not detected by immunohistochemical procedure, but mutant p53 and wild-type p53 stabilized by certain viral oncoproteins can accumulate to immunohistochemically demonstrable levels. Conventional pulmonary adenocarcinomas and bronchioalveolar carcinomas,...

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PMID: 8751332

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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