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Article

Intracellular targeting of lysosomal cathepsin D in COS cells.

Journal of biochemistry - 1 Nov 1995

Takeshima H, Sakaguchi M, Mihara K, Murakami K, Omura T

Abstract excerpt

Cathepsin D carries a mannose 6-phosphate sorting signal which is recognized by a specific mannose 6-phosphate receptor, presumably at the site of the trans Golgi network, which segregates cathepsin D from the secretory proteins, and results in targeting of the enzyme to the acidic prelysosomal compartments and lysosomes in mammalian cells. Recent evidence implies that another sorting signal resides within the...

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PMID: 8749316
DOI: 10.1093/jb/118.5.981

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Intracellular targeting of lysosomal cathepsin D in COS cells.PMID 8749316Read ↗

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