Article
An efficient strategy for detection of known and new mutations of the CYP2D6 gene using single strand conformation polymorphism analysis.
Pharmacogenetics - 1 Dec 1995
Broly F, Marez D, Sabbagh N, Legrand M, Millecamps S, Lo Guidice J M, Boone P, Meyer U A
Abstract excerpt
To detect mutations in the cytochrome P450 CYP2D6 gene (CYP2D6), we developed a strategy based on single-strand conformation polymorphism (SSCP) analysis of the gene amplified by polymerase chain reaction (PCR). The efficiency of the method was evaluated by analysing DNA samples from extensive me...
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