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Article

Maturation of neonatal human CD4 T cells: III. Role of B7 co-stimulation at priming.

International immunology - 1 Dec 1995

Yang L P, Demeure C E, Byun D G, Vezzio N, Delespesse G

Abstract excerpt

We previously reported that human naive CD4 T cells differentiate into effector cells producing type 1 (IL-2, IFN-gamma) and type 2 (IL-4, IL-5, IL-10) cytokines after priming with anti-CD3 mAb presented on irradiated CD32-transfected mouse L fibroblasts, in the absence of exogenous cytokine. Here we first show that the CD32 L fibroblasts act not only by cross-linking anti-CD3 mAb but also by providing a...

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PMID: 8746568
DOI: 10.1093/intimm/7.12.1987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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