Article
Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal.
The Journal of experimental medicine - 1 Apr 1993
Ranheim E A, Kipps T J
Abstract excerpt
Cognate interactions between antigen-presenting B and T cells play crucial roles in immunologic responses. T cells that have been activated via the crosslinking of CD3 are able to induce B cell proliferation and immunoglobulin secretion in a major histocompatibility complex-unrestricted and contact-dependent manner. We find that such activated human CD4+ T cells, but not control Ig-treated T cells, may induce...
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