Article
ICAM-1 and LFA-3 enhance the ability of anti-CD3 mAb to stimulate interferon gamma production in interleukin-2-activated T cells.
Cancer immunology, immunotherapy : CII - 1 Aug 1994
Chong A S, Jiang X L, Scuderi P, Lamas M, Graf L H
Abstract excerpt
Interleukin-2 (IL-2)-activated killer cells, also referred to as lymphokine-activated killer (LAK) cells, are stimulated by tumor cells to express cytotoxic activity and to also secrete cytokines such as interferon gamma (IFN gamma) and tumor necrosis factor alpha (TNF alpha). We previously repor...
Topics
- Antibodies, Monoclonal
- Antigens, CD
- Antigens, Differentiation, T-Lymphocyte
- CD2 Antigens
- CD3 Complex
- CD58 Antigens
- Cell Adhesion
- Cell Adhesion Molecules
- Humans
- Intercellular Adhesion Molecule-1
- Interferon-gamma
- Interleukin-2
- Killer Cells, Lymphokine-Activated
- Lymphocyte Activation