Neurotrophin-4/5 selectively protects nigral calbindin-containing neurons in rats with medial forebrain bundle transections.

doi:10.1016/0306-4522(95)00607-9

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Article

Neurotrophin-4/5 selectively protects nigral calbindin-containing neurons in rats with medial forebrain bundle transections.

Neuroscience - 1 Jun 1996

Alexi T, Hefti F

Abstract excerpt

Three neurotrophic factors associated with the nigrostriatal dopaminergic system were tested for their trophic potential to rescue degenerating substantia nigra dopaminergic neurons in adult rats with transections of the medial forebrain bundle. Axotomy of nigral dopaminergic neurons results in a...

Topics

Animals
Antibody Specificity
Calbindin 2
Calbindins
Fibroblast Growth Factor 2
Immunohistochemistry
Injections, Intraventricular
Male
Nerve Growth Factors
Nerve Tissue Proteins
Neurons
Neuroprotective Agents
Phenotype
Prosencephalon
Rats
Rats, Inbred F344
S100 Calcium Binding Protein G
Substantia Nigra

Source

Open in PubMed

Identifiers

PMID: 8735219
DOI: 10.1016/0306-4522(95)00607-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8735219-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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