Article
High diversity of poliovirus strains isolated from the central nervous system from patients with vaccine-associated paralytic poliomyelitis.
Journal of virology - 1 Dec 1994
Georgescu M M, Delpeyroux F, Tardy-Panit M, Balanant J, Combiescu M, Combiescu A A, Guillot S, Crainic R
Abstract excerpt
To establish the etiology of vaccine-associated paralytic poliomyelitis (VAPP), isolates from the central nervous system (CNS) from eight patients with VAPP were compared with stool isolates from the same patients. The vaccine (Sabin) origin was checked for all of the available isolates. Unique a...
Topics
- Animals
- Base Sequence
- Cell Line
- Chlorocebus aethiops
- DNA Primers
- Genetic Variation
- Humans
- Infant
- Mice
- Mice, Transgenic
- Molecular Sequence Data
- Poliomyelitis
- Poliovirus
- Poliovirus Vaccine, Oral
- Polymerase Chain Reaction