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Article

Scleroderma fibroblast phenotype is modulated by endothelial cell co-culture.

The Journal of rheumatology - 1 Apr 1996

Denton C P, Xu S, Welsh K I, Pearson J D, Black C M

Abstract excerpt

OBJECTIVE: We established a co-culture system to investigate endothelial cell-fibroblast interaction in scleroderma (systemic sclerosis, SSc). Such a system allows reciprocal interaction between these cells. The pattern of phenotypic modulation for normal and SSc fibroblasts in co-culture was compared. METHODS: A virally transformed human umbilical vein endothelial cell (HUVEC) derived cell line (1E-7) was...

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PMID: 8730117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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