Article
ras and p53 genes in male breast cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 1996
Dawson P J, Schroer K R, Wolman S R
Abstract excerpt
We have studied the roles of Ki-ras oncogene and p53 tumor suppressor gene in a series of 20 cases of male breast cancer and one papilloma of the male breast. Ki-ras was detected in 50-microns sections after digestion with proteinase K and SDS. DNA was amplified by polymerase chain reaction, dot blotted, and mutations were screened with labeled ras mutation-specific oligonucleotides. Wild-type and mutant p53...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.