Significantly increased frequency of the apolipoprotein E epsilon 4 allele in elderly non-demented leprosy patients.

doi:10.1016/0304-3940(96)12513-1

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Significantly increased frequency of the apolipoprotein E epsilon 4 allele in elderly non-demented leprosy patients.

Neuroscience letters - 5 Apr 1996

Endoh M, Ueki A, Takahashi K, Yamanaka H, Izumi S, Tabira T

Abstract excerpt

Apolipoprotein E (apo E) genotypes in 350 leprosy patients were examined and compared with those of 870 age-matched controls. The allelic frequencies of the apo E gene did not differ between demented patients with leprosy and controls. However, the frequency of apo E epsilon 4 allele was significantly higher in non-demented leprosy patients than in controls (P < 0.001). Of special interest is that the prevalence...

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Significantly increased frequency of the apolipoprotein E epsilon 4 allele in elderly non-demented leprosy patients.

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