Article
Characterization of streptomycin resistance mechanisms among Mycobacterium tuberculosis isolates from patients in New York City.
Antimicrobial agents and chemotherapy - 1 May 1996
Cooksey R C, Morlock G P, McQueen A, Glickman S E, Crawford J T
Abstract excerpt
From a collection of 367 isolates of Mycobacterium tuberculosis from patients in New York City in 1994, 45 isolates (12.3%) were resistant in vitro to 2 micrograms or more of streptomycin (SM) per ml. We further evaluated these isolates for levels of SM resistance and for mutations previously associated with resistance in the rpsL (S12 ribosomal protein) gene and the rrs (16S rRNA)-coding region. Twenty-four...
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