Article
Characterization of streptomycin resistance mechanisms among Mycobacterium tuberculosis isolates from patients in New York City.
Antimicrobial agents and chemotherapy - 1 May 1996
Cooksey R C, Morlock G P, McQueen A, Glickman S E, Crawford J T
Abstract excerpt
From a collection of 367 isolates of Mycobacterium tuberculosis from patients in New York City in 1994, 45 isolates (12.3%) were resistant in vitro to 2 micrograms or more of streptomycin (SM) per ml. We further evaluated these isolates for levels of SM resistance and for mutations previously ass...
Topics
- Antibiotics, Antitubercular
- DNA, Bacterial
- Drug Resistance, Microbial
- Genes, Bacterial
- Humans
- Mutation
- Mycobacterium tuberculosis
- New York City
- Point Mutation
- Polymorphism, Single-Stranded Conformational
- RNA, Ribosomal, 16S
- Streptomycin