Epigenetic control of a transposon-inactivated gene in Neurospora is dependent on DNA methylation.

doi:10.1093/genetics/143.1.137

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Article

Epigenetic control of a transposon-inactivated gene in Neurospora is dependent on DNA methylation.

Genetics - 1 May 1996

Cambareri E B, Foss H M, Rountree M R, Selker E U, Kinsey J A

Abstract excerpt

An unstable allele of the Neurospora am (GDH) gene resulting from integration of the retrotransposon Tad3-2 into 5' noncoding sequences was found in previous work. We report that reversion to Am+ depends on DNA methylation within and upstream of Tad. Levels of methylation were correlated with the...

Topics

Alleles
DNA Transposable Elements
DNA, Fungal
Genes, Fungal
Genetic Markers
Glutamate Dehydrogenase
Glycine
Methylation
Neurospora crassa
Phenotype
Restriction Mapping
Retroelements

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