Article
Cleavages induced by different metal ions in yeast tRNA(Phe) U59C60 mutants.
Biochemistry - 20 Aug 1996
Michałowski D, Wrzesinski J, Krzyzosiak W
Abstract excerpt
The U59 and C60 residues, which form the strong Pb(II) ion binding site in yeast tRNA(Phe), were systematically mutated, and the effects of individual mutations on cleavages induced by various metal ions were analyzed. It turned out that the presence of C60 is essential for efficient cleavage of...
Topics
- Base Sequence
- Endoribonucleases
- Hydrolysis
- Metals
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- RNA, Transfer, Phe
- Saccharomyces cerevisiae