Article
Endocytosis of chimeric influenza virus hemagglutinin proteins that lack a cytoplasmic recognition feature for coated pits.
The Journal of cell biology - 1 Jul 1996
Lazarovits J, Naim H Y, Rodriguez A C, Wang R H, Fire E, Bird C, Henis Y I, Roth M G
Abstract excerpt
The influenza virus A/Japan/305/57 hemagglutinin (HA) can be converted from a protein that is essentially excluded from coated pits into one that is internalized at approximately the rate of uptake of bulk membrane by replacing the HA transmembrane and cytoplasmic sequences with those of either o...
Topics
- Amino Acid Sequence
- Animals
- Binding Sites
- Cell Line
- Chlorocebus aethiops
- Cloning, Molecular
- Coated Pits, Cell-Membrane
- Cytoplasm
- Endocytosis
- Hemagglutinin Glycoproteins, Influenza Virus
- Hemagglutinins, Viral
- Humans
- Hypertonic Solutions
- Influenza A virus