Article
Participation of two Ser-Ser-Phe-Tyr repeats in interleukin-6 (IL-6)-binding sites of the human IL-6 receptor.
European journal of biochemistry - 15 Jun 1996
Kalai M, Montero-Julian F A, Grötzinger J, Wollmer A, Morelle D, Brochier J, Rose-John S, Heinrich P C, Brailly H, Content J
Abstract excerpt
The alpha-subunit of interleukin-6 (IL-6) receptor is a member of the hematopoietin receptor family. The alignment of its amino acid sequence with those of other members of this family (human somatotropin receptor/murine IL-3 receptor beta and human IL-2 receptor beta) has suggested that amino acids included in two SSFY repeats found in each of its hematopoietin receptor domains, contribute to the binding of the...
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