Article
The frequency of the haemochromatosis-associated genotype D6S265-1:D6S105-8 in blood donors.
British journal of haematology - 1 Jun 1996
Worwood M, Dorak M T, Nicklin S, Stone C, Pointon J, Darke C
Abstract excerpt
Homozygosity for HLA-A3 and the microsatellite markers D6S265 allele 1 and D6S105 allele 8 is associated with a high relative risk for genetic haemochromatosis-indeed we and others have suggested that a haplotype including D6S265-1, HLA-A3 and D6S105-8 is specific for haemochromatosis. To determi...
Topics
- Adult
- Aged
- Blood Donors
- Female
- Gene Frequency
- Genotype
- HLA-A3 Antigen
- Hemochromatosis
- Homozygote
- Humans
- Male
- Microsatellite Repeats
- Middle Aged