Article
The frequency of the haemochromatosis-associated genotype D6S265-1:D6S105-8 in blood donors.
British journal of haematology - 1 Jun 1996
Worwood M, Dorak M T, Nicklin S, Stone C, Pointon J, Darke C
Abstract excerpt
Homozygosity for HLA-A3 and the microsatellite markers D6S265 allele 1 and D6S105 allele 8 is associated with a high relative risk for genetic haemochromatosis-indeed we and others have suggested that a haplotype including D6S265-1, HLA-A3 and D6S105-8 is specific for haemochromatosis. To determine the frequency of this haplotype and examine its specificity for haemochromatosis we have analysed data from 7820...
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