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Article

The frequency of hemochromatosis-associated alleles is increased in British patients with sporadic porphyria cutanea tarda.

Hepatology (Baltimore, Md.) - 1 Jan 1997

Roberts A G, Whatley S D, Nicklin S, Worwood M, Pointon J J, Stone C, Elder G H

Abstract excerpt

The cause of the hepatic siderosis and iron overload that is common in porphyria cutanea tarda (PCT) is uncertain. Heterozygosity for genetic hemochromatosis has been supported by some studies of the association between the HLA-A3 antigen and porphyria cutanea tarda but not by others. The hemochromatosis gene is now believed to be located telomeric to HLA-A3 and close to the DNA microsatellite marker D6S1260. We...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Female
Ferritins
HLA-A3 Antigen
Haplotypes
Hemochromatosis
Humans
Iron
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Porphyria Cutanea Tarda

Transferrin

Source

Identifiers

PMID: 8985283
DOI: 10.1002/hep.510250129

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The frequency of hemochromatosis-associated alleles is increased in British patients with sporadic porphyria cutanea tarda.PMID 8985283Read ↗

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