Article
New polymorphic microsatellite markers place the haemochromatosis gene telomeric to D6S105.
Human molecular genetics - 1 Oct 1995
Raha-Chowdhury R, Bowen D J, Stone C, Pointon J J, Terwilliger J D, Shearman J D, Robson K J, Bomford A, Worwood M
Abstract excerpt
The haemochromatosis gene (HFE) is linked to both HLA-A and D6S105 on the short arm of chromosome 6 but these markers are separated by approximately 2 Mb of DNA. Most chromosomes carrying HFE have a common haplotype which extends from HLA-A to D6S105 and includes HLA-F. To localise the gene more precisely we have examined 10 microsatellite markers extending over a genetic distance of approximately 5 cM from...
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