Article
Alleles at D6S265 and D6S105 define a haemochromatosis-specific genotype.
British journal of haematology - 1 Apr 1994
Worwood M, Raha-Chowdhury R, Dorak M T, Darke C, Bowen D J, Burnett A K
Abstract excerpt
Hereditary haemochromatosis is an HLA-linked, recessive disorder with HLA-A3 a strong marker for the gene. We have identified molecular markers for two serologically indistinguishable subtypes of HLA-A3 and examined these in 42 patients with haemochromatosis. The common HLA-A3 subtype HLA-A*0301 (highly correlated with allele 1 of D6S265) was a slightly better marker for haemochromatosis (RR = 10.1, Chi2 = 30)...
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