Alleles at D6S265 and D6S105 define a haemochromatosis-specific genotype.

doi:10.1111/j.1365-2141.1994.tb04843.x

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Article

Alleles at D6S265 and D6S105 define a haemochromatosis-specific genotype.

British journal of haematology - 1 Apr 1994

Worwood M, Raha-Chowdhury R, Dorak M T, Darke C, Bowen D J, Burnett A K

Abstract excerpt

Hereditary haemochromatosis is an HLA-linked, recessive disorder with HLA-A3 a strong marker for the gene. We have identified molecular markers for two serologically indistinguishable subtypes of HLA-A3 and examined these in 42 patients with haemochromatosis. The common HLA-A3 subtype HLA-A*0301...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Alleles
Child
Genetic Markers
Genotype
HLA-A3 Antigen
Hemochromatosis
Homozygote
Humans
Middle Aged
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length

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