Article
Topological structure of the space of phenotypes: the case of RNA neutral networks.
PloS one - 1 Jan 2011
Aguirre Jacobo, Buldú Javier M, Stich Michael, Manrubia Susanna C
Abstract excerpt
The evolution and adaptation of molecular populations is constrained by the diversity accessible through mutational processes. RNA is a paradigmatic example of biopolymer where genotype (sequence) and phenotype (approximated by the secondary structure fold) are identified in a single molecule. The extreme redundancy of the genotype-phenotype map leads to large ensembles of RNA sequences that fold into the same...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.